HPE ProLiant DL380 Gen11 Rack Server – Xeon Gold 5416S, 128 GB DDR5, 6×3.84 TB SSD, MR408i‑o Controller
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  • Part number:HPE ProLiant DL380 Gen11
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HPE ProLiant DL380 Gen11 Rack Server – Xeon Gold 5416S, 128 GB DDR5, 6×3.84 TB SSD, MR408i‑o Controller

Keywords

HPE ProLiant DL380 Gen11, Xeon Gold 5416S, 128 GB DDR5 RDIMM, Kingston DC600M SSD, MR408i‑o storage controller

Description

The HPE ProLiant DL380 Gen11 is a versatile 2U rack server featuring 4th‑Gen Intel® Xeon® Scalable platform support — here configured with a single Intel® Xeon® Gold 5416S CPU (16 cores, 32 threads, 2.00 GHz base clock up to 4.00 GHz, 150 W TDP).

Configured with 128 GB of DDR5 RDIMM memory (8 × 16 GB modules at 4800 MT/s), it populates half of the available 32 DIMM slots. This memory configuration is fully supported on Gen11 servers with Xeon Gold 5416S processors.

Storage is handled via six Kingston DC600M 3.84 TB enterprise SATA SSDs in SFF bays, delivering mixed‑use performance and reliable endurance for demanding workloads.

Data redundancy and performance is managed via the HPE MR408i‑o Gen11 storage controller (OCP SPDM, x8 lanes, 4 GB cache) paired with an HPE Smart Storage Battery for write‑cache persistence.

The system supports up to three double‑wide or eight single‑wide GPGPUs, 1+1 redundant 1000 W hot‑plug power supplies, and features Broadcom BCM5719 4‑port 1 Gb BASE‑T OCP3 adapter, ideal for diverse compute and GPU‑accelerated workloads. A 3‑year with parts, labor, and on‑site warranty completes the enterprise‑grade package.

Key Features
  • Single Intel Xeon Gold 5416S: 16 cores / 32 threads, 2.00–4.00 GHz, 150 W TDP 
  • 128 GB DDR5 RDIMM (8 × 16 GB @ 4800 MT/s), supported on Gen11 DDR5 platforms 
  • Six Kingston DC600M 3.84 TB mixed‑use enterprise SSDs providing high throughput and endurance
  • HPE MR408i‑o Gen11 OCP SPDM controller with 4 GB cache and Smart Storage Battery support
  • Expandable GPU support: up to 2 dual‑wide or 3 single‑wide GPGPUs
  • Broadcom BCM5719 Quad‑port 1 Gb BASE‑T OCP3 network adapter
  • Redundant 1+1 HPE 1000 W Flex Slot hot‑plug power supplies (low halogen)
  • 3‑year warranty: parts, labor, and on‑site support
Configuration
ComponentSpecification
ChassisHPE ProLiant DL380 Gen11 2U Rack SFF Server
CPU1× Intel Xeon Gold 5416S (16‑core / 32‑thread, 2.00 – 4.00 GHz, 150 W)
Memory128 GB DDR5 RDIMM (8 × 16 GB @ 4800 MT/s, dual‑rank)
Storage Bays8× SFF SAS/SATA bays
Internal SSDs6 × Kingston DC600M 3.84 TB SATA SSD (mixed‑use)
Storage ControllerHPE MR408i‑o Gen11 x8 PCIe lanes, 4 GB cache, Smart Storage Battery
NetworkingBroadcom BCM5719 Quad‑port 1 Gb BASE‑T OCP3 adapter
GPU SupportSupports up to 2 double‑wide or 3 single‑wide GPGPU cards
Power SupplyRedundant (1+1) HPE 1000 W Flex Slot Hot‑Plug low halogen PSUs
Warranty3‑year parts, labor, and on‑site support
Compatibility
This configuration is fully compatible with HPE ProLiant DL380 Gen11 platform supporting 4th‑Gen Intel Xeon Scalable CPUs such as Xeon Gold 5416S. It supports DDR5 memory at up to 5600 MT/s and is validated for 16 GB DDR5‑4800 RDIMM modules in matched sets.

The MR408i‑o controller supports SAS/SATA drives in 8 SFF bays, and GPU expansion is available via PCIe Gen5 slots and OCP3 connectors (up to 8 single‑wide GPUs or 3 double‑wide) .

Usage Scenarios

This server is ideal for enterprise virtualization, database hosting, or mixed‑use storage workloads with high I/O reliability via Kingston SSDs. It’s particularly suited for GPU‑accelerated computing, AI/ML inference, or VDI deployments, given support for multiple GPGPUs.

The combination of high‑density DDR5 memory and a MR408i‑o controller ensures low-latency storage performance for mission-critical applications.

With redundant power supplies and on‑site support for 3 years, the system offers reliability for remote or continuously running environments.

The OCP3 network adapter and iLO 6/OneView support provide remote management, telemetry, firmware control, and integration into HPE GreenLake operations when scaled across hybrid infrastructure.

Frequently Asked Questions
Q1: Does the memory configuration support 128 GB with 4800 MT/s DDR5 RDIMM?
Yes — DL380 Gen11 supports DDR5 memory at 4800 MT/s and 5600 MT/s when matched modules are used. Installing 8× 16 GB DDR5‑4800 RDIMMs is fully supported with this Xeon Gold 5416S CPU platform.
Q2: How many GPUs can this chassis support?
Up to 2 double‑wide or 3 single‑wide GP GPUs are supported via available PCIe Gen5 and OCP3 slots, ideal for acceleration or visualization use cases.
Q3: Is the MR408i‑o controller suitable for SSD RAID?
Yes — the MR408i‑o Gen11 controller with 4 GB cache and Smart Storage Battery supports SAS/SATA RAID configurations across the 8 SFF bays, ensuring reliable SSD caching and redundancy.
Q4: What warranty and service coverage is included?
This system includes HPE’s standard 3‑year warranty covering parts, labor, and on‑site support for comprehensive enterprise reliability.

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